zyntha.

Brain-tumor research, read for you.

Zyntha is a patient-driven intelligence platform for brain-tumor communities — patients, caregivers, and clinicians. We monitor over a thousand sources of oncology research from around the world, surface what actually matters for your tumor type, and send it to you every other week in plain language. With sources cited.

Free, bi-weekly. Unsubscribe with one click. We never sell your data.
1,000+
Sources monitored worldwide
9
Brain-tumor portals
Bi-weekly
Digest cadence, every other Sunday
100%
Free, ad-free, never sold
Who Zyntha is for

Three audiences. One careful pipeline.

Brain-tumor news lands differently depending on who you are. The digest is shaped for each.

🧠

Patients

Recent research that affects the treatments and trials available to you — explained in plain language, sources always cited.

  • FDA approvals and label updates for your tumor type
  • Trials recruiting near you, with eligibility in plain English
  • Questions to bring to your oncologist
💛

Caregivers

Practical updates without the noise. What's changed, what it might mean for treatment, and what to watch for next visit.

  • What this means for treatment in real terms
  • Side-effect research and supportive care
  • Resources for the people supporting the person
🩺

Clinicians

A weekly second pair of eyes on neuro-oncology. Phase results, guideline updates, molecular and trial-design signals — across the world's literature.

  • Phase 2 / 3 readouts and meta-analyses
  • Molecular biomarker and subtype updates
  • Cross-institutional and global trial signal
How it works

From a thousand journals to your inbox.

A four-step pipeline runs continuously in the background. By the time a story reaches your inbox, it has been read, scored, summarized, and cited.

01

We monitor 1,000+ sources every few hours

PubMed, EuropePMC, NEJM, JCO, JAMA Oncology, Lancet Oncology, Nature Cancer, STAT, Endpoints, hospital newsrooms (MSK, MD Anderson, Cleveland Clinic, Dana-Farber, 71+ NCI-designated centers), conference proceedings, ASCO, ASH, SNO, the FDA, and the ClinicalTrials.gov registry. Across journals, news outlets, and trial registries — every few hours.

02

We score each item for relevance

Every paper, news article, and trial is read against a brain-tumor-specific rubric and tagged by tumor type, molecular subtype, evidence level (Phase 3 / Phase 2 / preclinical / review), and treatment category. Off-topic content and incidental keyword hits are filtered out before anything gets near your inbox.

03

We rewrite it in plain language

Each item becomes a short summary, with the key findings as bullets and a "what this means" sentence translating the research into clinical or patient-facing implications. Compliance-reviewed copy. Source always cited and clickable.

04

You get the top stories for your tumor type, every other week

The digest lands every other Sunday morning. Personalized to the tumor portal you pick at signup, with the option to switch portals or unsubscribe at any time. One email. No tracking pixels selling you anything.

What you get

Every item, the same careful shape.

A real entry from a recent issue. Title, summary, key findings, what it means, source. That's it.

Glioma · Trial spotlight · Phase 3
Vorasidenib extends progression-free survival in IDH-mutant glioma.

The INDIGO trial demonstrated that vorasidenib, an oral IDH1/2 inhibitor, more than doubled progression-free survival compared with placebo in patients with recurrent IDH-mutant grade 2 glioma after surgery.

Key findings
  • Median PFS: 27.7 months on vorasidenib vs 11.1 months on placebo
  • Time to next intervention significantly delayed
  • Adverse event profile manageable; mostly elevated liver enzymes
What this means: First targeted therapy approved specifically for IDH-mutant grade 2 glioma. May delay the need for chemoradiation in eligible patients. Talk to your neuro-oncology team about whether IDH-mutation testing was part of your workup.
📰 Source: New England Journal of Medicine — read the original →
Tumor focus

Nine portals. Yours, specifically.

Each tumor type has its own newsletter, its own keyword model, and its own trial pipeline. You pick which one shows up in your inbox.

Glioma
Glioblastoma · Astrocytoma · Oligodendroglioma
Meningioma
WHO grade I–III · Skull-base techniques
Medulloblastoma
SHH · WNT · Group 3 · Group 4
Ependymoma
Posterior fossa · Supratentorial · Spinal
Schwannoma
Vestibular · NF2 · Schwannomatosis
Pituitary
Adenoma · Cushing · Acromegaly
Spinal Cord
Chordoma · Intramedullary tumors
Brain Metastases
Lung · Breast · Melanoma · GI · Renal
CNS Lymphoma
PCNSL · Secondary CNS · CAR-T
Trust foundation

The boring stuff that actually matters.

A brain-tumor community is one of the most personal spaces a person ever joins. Every architectural decision starts from the assumption that the trust we ask for is real.

Sources always cited. Every summary links back to the original publisher. No content without a verifiable source.
Compliance-reviewed. Clinical content always carries an "information only — not medical advice" line. We never imply we replace your care team.
Privacy first. Your email is used to send the digest. We do not sell, share, or rent it. Unsubscribe ends storage of your data.
Human-edited. Editorial review, verified healthcare-professional badges, and a moderation team behind every public surface.

Join the digest before launch.

The full Zyntha platform — community, in-app digest, personal health tracking, trial matching — opens soon. Subscribe now and the first edition lands in your inbox today.